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It is non-symmetrical and usually tends to affect dorsal roots of the spine.It is more stable, less erratic, and responds well to topical treatments.

Oxsoralen is highly phototoxic (likely to cause a sunburn), and the phototoxicity lasts for 3 days or more.

Medical history:- Four options are currently available for the treatment of vitiligo: sunscreens; cover-up; restoration of normal skin color; and bleaching of normal skin with topical creams to remove normal skin pigment to make an even color.

The two goals of sunscreen treatments are: to protect unpigmented involved skin from sunburn reaction and to limit the tanning of normal pigmented skin.

Restoration of normal skin color can take the form of spot treatments or whole body treatment.

Initial treatment with certain topical corticosteroid creams is practical, simple, and safe.

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  1. This thriving social center of Spain's capital has a semicircular shape, its ancient origins date back to the 15th century and to the reign of Charles I who ordered a gate to be built for better access into the town; soon it became a meeting point and new buildings were built, originally to serve political functions, all around the '' (puerta) that, starting from the 15th century, was the entrance gate to the capital, its name, Spanish for 'Gate of the Sun' derives from this city gate decorated with a symbolic sun; over the centuries Madrid grew rapidly, the square was considerably enlarged and new elegant and imposing buildings were erected, the House of the Post Office (Real Casa de Correos, 1768), a work of the architect Jacques Marquet, is still today a splendid example of this. , but the exact distance : 5.63 mi (9.06 km)--- from Wanda Metropolitano Stadium---to Puerta del Sol, Madrid, Spain.